Secure genome-wide association analysis using multiparty computation

Cho et al. ‘describe a protocol for large-scale genome-wide analysis that facilitates quality control and population stratification correction […] while maintaining the confidentiality of underlying genotypes and phenotypes. […] This approach may help to make currently restricted data available to the scientific community and could potentially enable secure genome crowdsourcing, allowing individuals to contribute their genomes to a study without compromising their privacy.’

  • Cho H, Wu DJ, Berger B
    Secure genome-wide association analysis using multiparty computation
    Nature Biotechnology. 2018. Online May 07.
    (Abstract, PDF, Source Code)

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