Deriving genomic diagnoses without revealing patient genomes

Jagadeesh et al. encode an individuals functional variants as a binary vector. They then use Yao’s protocol to identify relevant coincidences between pools of such vectors engaging in secure multiparty computation.

  • Jagadeesh KA, Wu DJ, Birgmeier JA, Boneh D, Bejerano G
    Deriving genomic diagnoses without revealing patient genomes
    Science. 2017. Volume 357. Issue 6352. Pages 692–695.
    (Abstract, PDF, Source Code)